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Memantine or amantadine?
The inclusion of NMDA antagonists in chronic pain management has proven essential in the management of a variety of chronic pain. The...
zeropainphilosophy
3 min read


The quest to reduce volatile agent use
Optimising intra-operative analgesia Veterinary practitioners are currently facing a shortage of isoflurane, leading many to wonder how...
zeropainphilosophy
6 min read


Basics of local anaesthesia
The first reported use of local anaesthetic for surgical purposes was by a Peruvian army surgeon, that drug being cocaine, derived from...
zeropainphilosophy
5 min read


Low dose ketamine analgesia
The most common NMDA antagonist we use in every day practice is ketamine which we use as an infusion or bolus. Ketamine is a modulator of...
zeropainphilosophy
4 min read


Feline maladaptive pain
The recent publication of a review entitled ‘Chronic maladaptive pain in cats: A review of current and future drug treatment options’ by...
zeropainphilosophy
4 min read


Grapiprant: need to know
Grapiprant is a novel analgesic licensed for managing pain associated with osteoarthritis (OA) in dogs. It launched in the UK early 2019,...
zeropainphilosophy
4 min read


Opioids in dogs and cats
Opioids are the mainstay of analgesia in veterinary practice and should be considered as first line for all animals in pain. Secondly, we...
zeropainphilosophy
5 min read


Sedation for the painful behaviour case - dogs & cats
Medication protocols for emotionally challenged dogs during veterinary visits and procedures from Zero Pain Philosophy and Behavioural...
zeropainphilosophy
5 min read


September is chronic pain month
September is designated as pain month for the American Chronic Pain Association. The aim is to increase the awareness of painful...
zeropainphilosophy
3 min read


NSAIDs or multimodal for OA?
A common question I am asked is should I go multimodal from day one in osteoarthritis with my analgesics? Let's be clear - NSAIDs are...
zeropainphilosophy
3 min read


So what is neuropathic pain?
The International Association for the Study of Pain (IASP) definition of neuropathic pain is; 'Pain initiated or caused by a primary...
zeropainphilosophy
11 min read


Amantadine for chronic pain
Amantadine is an oral NMDA antagonist used for the management of chronic pain in dogs and cats. Amantadine has pharmacological actions as...
zeropainphilosophy
4 min read


Pain recognition & scoring
What is pain? The International Association for the Study of Pain (IASP) definition of pain is; Pain is a complex sensory and emotional...
zeropainphilosophy
5 min read


How does acupuncture work?
There are two approaches to the teaching and theory of acupuncture (AP), traditional chinese medicine (TCM) and the western scientific...
zeropainphilosophy
3 min read


Paracetamol for long term use
Paracetamol is useful as an alternative to NSAIDs in dogs that will not tolerate an NSAID or as an adjunct to NSAIDs in chronic pain....
zeropainphilosophy
3 min read


Intra-articular Analgesia
Options for peri-operative intra-articular (IA) analgesics are opioids or local anaesthetics. Over recent years concerns have been raised...
zeropainphilosophy
4 min read


Regional Anaesthesia for Stifle Surgery
With the latest evidence showing the superiority of local anaesthetics over opioids for patient comfort, the following discussion focuses...
zeropainphilosophy
4 min read


Epidural Analgesia
Epidural analgesia (or more anatomically, extradural) is used to provide analgesia to the pelvic limbs but will also afford analgesia to...
zeropainphilosophy
4 min read


Moving on from Pre-emptive Analgesia
Pre-emptive analgesia has been defined as ‘an antinociceptive treatment that prevents establishment of altered central processing of...
zeropainphilosophy
4 min read
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